Cialis a salerno

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Cialis

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Generic name:[cialis]Drug class:

Medically reviewed by. Last updated on Nov 27, 2024.

What is Cialis?

Cialis (tadalafil) is a prescription drug used to treat erectile dysfunction (impotence) in men. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. The active ingredient of Cialis is tadalafil, which works by relaxing the muscles in the penis, thereby increasing blood flow into the area.

Cialis is prescribed to men between the ages of 18 and 65 who have erectile dysfunction. It is also used for the treatment of benign prostatic hyperplasia (enlarged prostate).

The most common side effects of Cialis include headache, back pain, muscle aches, flushing, nasal congestion, indigestion, and back pain.

Cialis is approved for use by doctors only. You should not take Cialis if you are taking nitrates, are pregnant, or breast-feeding. Tell your doctor if you have any of these conditions:chest pain;or if you have ever had an allergic reaction to any of the following ingredients:any medicines, including prescription and non-prescription Cialis tablets (for the treatment of erectile dysfunction);orliver problems;or if you are under 18 years of age or 65 years old.

Cialis may cause serious side effects, including:

  • flushing;
  • irregular heartbeat;
  • loss of consciousness;
  • slow or irregular breathing;
  • headache;
  • severe stomach pain;
  • severe dizziness;
  • seizures; or
  • decreased sexual ability.

You should not use Cialis if you are taking nitrates, are pregnant, or breast-feeding.

Cialis may increase your blood pressure, and this may cause symptoms such as:

  • blocked nose;
  • trouble breathing;
  • confusion;
  • nausea;
  • stuffy nose; or
  • nervousness or restlessness.

Cialis may also cause a rare but serious condition called "benign prostatic hyperplasia." This condition may affect some men at any age and can be fatal. If you have any of the following symptoms, call your doctor at once:

  • fainting;
  • shortness of breath;
  • fast or irregular heartbeat;
  • seizures.

You should not use Cialis if you also take nitrates or are taking alpha-blockers to treat angina (chest pain). Alpha-blockers may increase your blood pressure.

You should not take Cialis if you also take other medications that make you more sensitive to the effects of the drug. Tell your doctor if you are taking any of the following:

  • methscopolamine;
  • medicine used to treat headache, including aspirin, ibuprofen, and certain heart medications;
  • medicine used to treat high blood pressure, including medicines for cough;
  • medicine used to treat a condition called pulmonary hypertension;
  • medicine used to treat erectile dysfunction; or
  • medicine used to treat pulmonary hypertension.

IMPORTANT NOTE:The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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The Food and Drug Administration has approved the use of tadalafil (the active ingredient in Cialis) for the treatment of erectile dysfunction in men who have had surgery on the penis, according to the results of a new study.

The findings of the study, released in a joint announcement by the U. S. Food and Drug Administration and a federal panel of scientists, were published Monday in theArchives of Internal Medicine. The FDA is expected to issue its first decision on the use of tadalafil (the active ingredient in Cialis) for the treatment of erectile dysfunction in men who have had surgery on the penis.

The study involved more than 1,300 men from the United States with erectile dysfunction, a condition where a man experiences difficulty getting or keeping an erection during sexual activity. The researchers looked at data from more than one hundred thousand men between the ages of 40 and 70 who had undergone a penis surgery.

The FDA approved the use of tadalafil in August in the United States, after it had issued an alert about the risks of taking the medication. But the agency's decision to approve the use of tadalafil will only apply to men who have taken the medication for the first time in as many years.

Dr. John Kline, director of the FDA's Center for Drug Evaluation and Research, said the study's results "provide important information about the potential for tadalafil to be used as a treatment option for patients with erectile dysfunction who have a history of priapism, priapism or other related conditions."

The FDA is reviewing the results of the study and will decide whether to approve the use of tadalafil for the treatment of erectile dysfunction, he added. The FDA will also decide whether to approve the use of tadalafil for the treatment of erectile dysfunction in men who have a history of priapism.

The study, which was funded by GlaxoSmithKline, was conducted by researchers at the National Institutes of Health and the U. Food and Drug Administration.

The study was published in theon Wednesday.

"This is one of those studies that we want to do in the first place," said Dr. Jonathan Mermin, the study's lead author. "The FDA has approved the use of tadalafil for the treatment of erectile dysfunction in men who have had surgery on the penis."

Tadalafil is a prescription medication that is also sometimes known as a "nitric oxide." Nitric oxide is a chemical produced by the heart and nervous system that can cause symptoms such as a burning sensation in the chest, pain or warmth in the head, and swelling of the arms, legs and ankles. It can also damage the kidneys.

The use of tadalafil for erectile dysfunction in men who have had surgery on the penis may help prevent the symptoms from returning or becoming worse. But it's not a cure, Dr. Kline said.

Tadalafil is available as a generic, but it's not available to men who have never had surgery on the penis. The FDA hasn't approved the use of tadalafil for the treatment of erectile dysfunction in men who have had surgery on the penis, but the FDA has approved the use of tadalafil for the treatment of erectile dysfunction in men who have had surgery on the penis.

The FDA will decide whether to approve the use of tadalafil for the treatment of erectile dysfunction in men who have a history of priapism, priapism or other related conditions.

The study was conducted by researchers at the National Institutes of Health and the U.

The researchers reviewed data from more than 1,500 men who have undergone a penis surgery between the ages of 40 and 70 who had been treated for erectile dysfunction at least once in as many years.

They found that most men taking tadalafil reported having taken it before having had surgery on the penis.